Parents

Oocyte Donation for Early Menopause or POI in India

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Short answer. Oocyte donation for early menopause or premature ovarian insufficiency (POI) is lawful in India and is one of the established ways for these women to carry a pregnancy. The eggs come from a screened donor through a registered ART Bank, and the embryo is placed in your own womb. Whether it is right for you is a decision you make with your doctor, after tests on your general health and your uterus.

What are POI and early menopause?

POI means the ovaries stop working normally before the age of 40. Periods become irregular or stop, and the hormone FSH rises. The 2024 international guideline from ESHRE, ASRM, CRE WHiRL and IMS says one raised FSH level above 25 IU/L, together with disordered periods, is enough to make the diagnosis. Where the picture is unclear, the doctor may repeat FSH or check AMH. The same guideline puts the frequency of POI at about 3.5% of women, higher than was once thought.

Early menopause is menopause between 40 and 45. Both can come as a shock, often at an age when friends are having their first child. It is normal to grieve before you think about treatment.

It is important that you have had a detailed discussion with your partner and with the counsellor. At Zoi we always have a counsellor who guides you through the pros, the cons and the after effects of going ahead with an oocyte donor. The programme is simple and effective, but it brings a great many questions, so we always advise counselling.

Can I still try with my own eggs?

Sometimes. A small number of women with POI still release an egg now and then and conceive naturally, which is why the diagnosis is not quite the same as menopause. Your doctor looks at your history, your hormone levels and your scan, and tells you honestly what your own ovaries can still offer.

At Zoi we do not push anyone towards a donor cycle without a medically valid reason. If there is still a reasonable chance with your own eggs, your doctor will say so. If there is not, donor eggs may give you the best chance of a pregnancy. Our page on own eggs and donor eggs covers the legal side of that choice.

Woman doctor in a white coat explaining a report to a couple at a clinic desk
Representative image, not a real clinic team member

Which tests come before donor eggs?

POI affects more than fertility, so the first visit is about your health as a whole. The 2024 guideline recommends looking for a cause, including a Fragile X premutation test for every woman with POI. Your doctor may also suggest:

CheckWhy it matters
Hormone levels and thyroidConfirms the diagnosis and looks for linked conditions
Genetic tests, including Fragile XLooks for a cause that may matter for your family
Bone densityLow oestrogen affects bone health
Heart and blood pressurePregnancy places extra load on the heart
Uterus scanThe womb must be ready to carry the pregnancy

Many women with POI also need hormone therapy for their general health, and this continues alongside fertility planning.

Four stages of an IVF cycle in a circle: Stimulation, Retrieval, Fertilisation, Transfer

How does oocyte donation for early menopause or POI work?

Because your ovaries are not producing eggs, your womb is prepared with oestrogen and then progesterone, so that its lining is ready when the embryo is placed. A screened donor goes through stimulation and egg retrieval at a registered ART clinic. Her eggs are fertilised with your husband’s sperm, and an embryo is transferred to your uterus. The steps are set out in our donor egg IVF steps, consents and insurance guide.

The ART Act adds clear protections:

  • The donor is a woman aged 23 to 35 and donates once in her life (Act s.27(2)(b), s.27(4)).
  • Each donor is supplied to one commissioning couple or woman only (Act s.27(3)).
  • She gives written informed consent, and you buy 12 months of insurance for her (Act s.22(1); Rules r.12, r.13).
  • The donor gives up all parental rights, and the child is deemed your biological child (Act s.31).

You also need to be within the Act’s age limit for treatment: a woman above 21 and below 50 (Act s.21(g)). Our post on donor eggs after 40 explains the age rules in detail.

Who decides, and how do we choose a donor?

You decide, with your doctor. Our Medical Director, Dr Yashodhara Mhatre, reviews your reports and talks you through the options before any donor is matched. Donor profiles never show her name, contact details or photo, and your coordinator goes through them with you. See how an Indian egg donor reaches a family through a registered ART Bank, and read our guide to egg donation law in India.

Book a private consultation. If you have been told you have POI or early menopause, bring your reports and let us go through them with you calmly. Book a private consultation

Questions

Can a woman with POI get pregnant with donor eggs?

Yes, many can. The embryo made from donor eggs is placed in her own uterus after it has been prepared with hormones. Her doctor decides whether pregnancy is safe for her.

Is oocyte donation for early menopause legal in India?

Yes, through a registered ART Bank, for a woman above 21 and below 50 (Act s.21(g), s.27(1)).

Do I need tests before donor eggs if I have POI?

Yes. The 2024 international guideline recommends looking for a cause, including a Fragile X premutation test, and checking bone and heart health.

Can I still use my own eggs with POI?

Sometimes. A small number of women with POI conceive with their own eggs. Your doctor tells you honestly what your ovaries can still offer.

Will the child be legally mine?

Yes. The child born through ART is deemed the biological child of the commissioning couple, and the donor gives up all parental rights (Act s.31).

References

  • Panay N, Anderson RA, Bennie A, et al. Evidence based guideline: premature ovarian insufficiency. ESHRE, ASRM, CRE WHiRL and IMS Guideline Group on POI. Human Reproduction Open 2024(4): hoae065. doi 10.1093/hropen/hoae065.
  • Assisted Reproductive Technology (Regulation) Act, 2021 (Act No. 42 of 2021): sections 21(g), 22(1), 27(1), 27(2)(b), 27(3), 27(4), 31.
  • Assisted Reproductive Technology (Regulation) Rules, 2022 (G.S.R. 419(E), 7 June 2022): rules 12 and 13.

This page explains the law and the medical guidance as published. It is not medical or legal advice. Your doctor decides what is right for you.

Thinking of donating?
Four questions, no names, under a minute.

Dr Yashodhara Mhatre, Medical Director, Zoi Fertility

Reviewed by Dr Yashodhara Mhatre, MBBS, MD, ART Fellow, Medical Director, Zoi Fertility.
This guide is general information, not medical or legal advice for your case.

Related guides

Indian woman in a cream kurta and plum dupatta smiling in a bright clinic corridor
Representative image

Indian Egg Donor: A Guide for USA, UK and Canada

Questions about egg donation?

A coordinator will call you back, in confidence.
Your IVF cycle takes place at our registered Level 2 ART clinic, with a registered donor from our ART Bank.